Questions
Straight answers.
Results, side effects, who it's for, ordering and delivery. Everything people ask, in one place.
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Results
What to expect, and how we know.
How much weight will I lose?
In the main trial, people on the highest dose lost 20.9% of their body weight on average after 72 weeks. Results vary from person to person. Use the goal calculator to see a date for your own goal.
Is tirzepatide better than semaglutide?
In a head-to-head trial, tirzepatide beat semaglutide: 20.2% against 13.7% of body weight lost at 72 weeks. That is about 47% more. Read the full comparison.
How does it work?
Tirzepatide acts on two gut hormones, GLP-1 and GIP. The effect is less hunger, feeling full sooner and steadier blood sugar. Eating less stops being a fight. The science page explains more.
Where do the figures come from?
From two published trials. SURMOUNT-1 (NEJM, 2022) found 20.9% at the highest dose after 72 weeks. SURMOUNT-5 (NEJM, 2025) compared tirzepatide with semaglutide.
Is a result guaranteed?
No. Results vary. Trial figures are averages, not promises. The goal tool shows an optimistic pace. It assumes you take every weekly dose and step up as planned.
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The treatment and side effects
What you inject, how often, and what to watch for.
What is tirzepatide?
Tirzepatide is the weight-loss treatment. It arrives as sealed weekly injections, one each week.
How often do I take it?
One injection a week, at home. It takes about a minute. The quick-start guide in your box shows you each step.
Does the injection hurt?
Most people barely feel it. The needle is very fine and goes just under the skin of your tummy or thigh.
What doses are there?
You start on 2.5 mg. You can step up every 4 weeks: 2.5, 5, 7.5, 10, 12.5, then 15 mg. You step up when you are ready, not before.
What are the common side effects?
Feeling sick, feeling full, constipation and diarrhoea. They are usually mild and fade over weeks. Starting on 2.5 mg and stepping up slowly helps.
When should I get urgent help?
Go to the nearest hospital straight away for severe stomach pain that won't go away, signs of an allergic reaction, or severe dehydration. Do not wait. More on the safety page.
Does it affect the contraceptive pill?
It can. Tirzepatide can change how well the pill works. Use a barrier method, such as condoms, for 4 weeks after you start and after each dose step.
Can I take it with anything else I take?
Tell us everything you take when you answer the questions. We look more closely at people on insulin or sulfonylureas. It may still be fine.
What if I miss a dose?
Your quick-start guide explains what to do. Do not take two doses together to catch up.
Is it safe?
Like any treatment, it has side effects, and it is not right for everyone. That is why we check your answers before anything is sent. If it isn't safe for you, you get a full refund.
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Eligibility
Who it suits, and who it does not.
Who can use Second Cure?
Adults aged 18 and over. You need a BMI of 30 or more, or a BMI of 27 or more with a weight-related condition. Try the BMI checker.
Which conditions count as weight-related?
Type 2 diabetes, high blood pressure, high cholesterol, sleep apnoea, PCOS, heart disease and fatty liver.
How do I work out my BMI?
Divide your weight in kilograms by your height in metres, squared. Or use the BMI checker, which does the sums for you.
Who is it not suitable for?
Pregnant, breastfeeding or trying to conceive. Also past pancreatitis, type 1 diabetes, or a history of an eating disorder. Also personal or family history of medullary thyroid cancer, or MEN2.
What do you look at more closely?
It may still be fine. We look more closely at: gallbladder problems, a past severe allergic reaction, upcoming surgery, diabetic eye disease, serious stomach or bowel conditions, kidney disease, low mood, age over 75, and insulin or sulfonylureas.
My BMI is between 27 and 30. Can I still start?
Yes, if you also have a weight-related condition from the list above. Without one, you are unlikely to qualify.
Is there an age limit?
You must be 18 or over. If you are over 75, we look more closely at your answers.
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Ordering and paying
Prices, payment, refunds and what happens next.
How much does it cost?
Prices are per 4 weeks: 2.5 mg ₦325,000, 5 mg ₦375,000, 7.5 mg ₦425,000, 10 mg ₦475,000, 12.5 mg ₦525,000, 15 mg ₦575,000. Delivery in Abuja is not included. See pricing.
What is the 8-week starter?
2.5 mg, then 5 mg, for ₦599,000 for 8 weekly injections. Month 1 lets your body adjust, month 2 moves to the stronger dose. It is our recommended start.
How does ordering work?
Answer a few questions, about 5 minutes on your phone. Choose your plan and pay. We check your answers, then it arrives cold. No appointments, no queues. See how it works.
When do I pay?
At checkout. Then we check your answers before anything is sent.
What if it isn't safe for me?
You get a full refund. We check your answers before anything is sent.
Do I have to subscribe?
No subscription and no auto-renew. You buy one order at a time. A week before your last dose, we email a reminder with a one-tap reorder link.
Can I stop any time?
Yes. Nothing renews, so you stop by not reordering.
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Delivery and storage
Where we deliver, what arrives and how to keep it.
Where do you deliver?
Abuja only for now. Delivery is not included. It depends on where you are in Abuja and is shown at checkout.
What is in the box?
4 weekly injections, each sealed in its own carton. Also 4 alcohol wipes, a cool pack and a quick-start guide. See everything in the box.
How is it kept cold?
It is kept at 2 to 8°C from our fridge to your door. A cool pack travels in the box.
What do I check when it arrives?
Check the seal on each box isn't broken. If it is, don't use that box and message us.
What do I do when it arrives?
Put everything in the fridge straight away. Then follow the injection guide when you are ready for your first dose.
Can I put it in the freezer?
No. Store it in the fridge, not the freezer.
How often will a delivery come?
Each order of 4 weeks arrives in one chilled box. The 8-week starter comes as two chilled deliveries.
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Switching from another provider
Already on tirzepatide? Carry on where you are.
I'm already on tirzepatide. Can I switch to you?
Yes. Carry on at your dose from ₦375,000. You upload a photo of your last box or label.
Do I have to restart at 2.5 mg?
Not if you are already on tirzepatide. Anyone new to it starts at 2.5 mg.
What do you need to see?
A photo of your last box or label. You upload it as you answer the questions.
What will it cost at my dose?
Your price follows your dose, from ₦375,000 at 5 mg to ₦575,000 at 15 mg. Every dose is on the pricing page.
What if I use a different GLP-1 treatment?
The carry-on route is for tirzepatide. Answer the questions and we will show you where you start. The comparison page shows how they differ.
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Your account
Reordering, changing dose and your details.
How do I reorder?
Use the one-tap link in your reminder email. We send it a week before your last dose. You can also log in.
Can I change my dose?
Yes. You can step up every 4 weeks when you are ready. Choose your next dose when you reorder.
How is my information used?
We use your answers to check it is safe for you before anything is sent. The rest is in our privacy policy.
Ready when you are.
Five minutes of questions. If it isn't safe for you, you get a full refund.
Still stuck? Email hello@secondcure.com